Location of the Antidepressant Binding Site in the Serotonin Transporter: IMPORTANCE OF SER-438 IN RECOGNITION OF CITALOPRAM AND TRICYCLIC ANTIDEPRESSANTS

The serotonin transporter (SERT) regulates extracellular levels of serotonin (5-hydroxytryptamine, 5HT) in the brain by transporting 5HT into neurons and glial cells. The human SERT (hSERT) is the primary target for drugs used in the treatment of emotional disorders, including depression. hSERT belo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Andersen, Jacob, Taboureau, Olivier, Hansen, Kasper B., Olsen, Lars, Egebjerg, Jan, Strømgaard, Kristian, Kristensen, Anders S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665081/
https://ncbi.nlm.nih.gov/pubmed/19213730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806907200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados