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Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter
The transporters for norepinephrine and dopamine (NET and DAT, respectively) constitute the molecular targets for recreational drugs and therapeutics used in the treatment of psychiatric disorders. Despite a strikingly similar amino acid sequence and predicted topology between these transporters, so...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621520/ https://ncbi.nlm.nih.gov/pubmed/26503701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15650 |
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