Reversing established sepsis with antagonists of endogenous high-mobility group box 1

Despite significant advances in intensive care therapy and antibiotics, severe sepsis accounts for 9% of all deaths in the United States annually. The pathological sequelae of sepsis are characterized by a systemic inflammatory response, but experimental therapeutics that target specific early infla...

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Bibliographic Details
Main Authors:	Yang, Huan, Ochani, Mahendar, Li, Jianhua, Qiang, Xiaoling, Tanovic, Mahira, Harris, Helena E., Susarla, Srinivas M., Ulloa, Luis, Wang, Hong, DiRaimo, Robert, Czura, Christopher J., Wang, Haichao, Roth, Jesse, Warren, H. Shaw, Fink, Mitchell P., Fenton, Matthew J., Andersson, Ulf, Tracey, Kevin J.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 2004
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC314179/ https://ncbi.nlm.nih.gov/pubmed/14695889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2434651100
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Reversing established sepsis with antagonists of endogenous high-mobility group box 1

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