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High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule

High mobility group box protein 1 (HMGB1) is an evolutionary ancient nuclear protein that exerts divergent biological tasks inside and outside of cells. The functions of HMGB1 depend on location, binding partners and redox states of the molecule. In the nucleus, HMGB1 organizes DNA and nucleosomes a...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Yang, Huan, Wang, Haichao, Chavan, Sangeeta S, Andersson, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661054/
https://ncbi.nlm.nih.gov/pubmed/26605648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00087
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