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High Mobility Group Box Protein 1 (HMGB1)-Partner Molecule Complexes Enhance Cytokine Production by Signaling Through the Partner Molecule Receptor

The nuclear protein high mobility group box protein 1 (HMGB1) promotes inflammation upon extracellular release. HMGB1 induces proinflammatory cytokine production in macrophages via Toll-like receptor (TLR)-4 signaling in a redox-dependent fashion. Independent of its redox state and endogenous cytoki...

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Autors principals: Hreggvidsdóttir, Hulda Sigridur, Lundberg, Anna M, Aveberger, Ann-Charlotte, Klevenvall, Lena, Andersson, Ulf, Harris, Helena Erlandsson
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320135/
https://ncbi.nlm.nih.gov/pubmed/22076468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00327
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