Reversing established sepsis with antagonists of endogenous high-mobility group box 1

Despite significant advances in intensive care therapy and antibiotics, severe sepsis accounts for 9% of all deaths in the United States annually. The pathological sequelae of sepsis are characterized by a systemic inflammatory response, but experimental therapeutics that target specific early infla...

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Hlavní autoři: Yang, Huan, Ochani, Mahendar, Li, Jianhua, Qiang, Xiaoling, Tanovic, Mahira, Harris, Helena E., Susarla, Srinivas M., Ulloa, Luis, Wang, Hong, DiRaimo, Robert, Czura, Christopher J., Wang, Haichao, Roth, Jesse, Warren, H. Shaw, Fink, Mitchell P., Fenton, Matthew J., Andersson, Ulf, Tracey, Kevin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC314179/
https://ncbi.nlm.nih.gov/pubmed/14695889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2434651100
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