Reversing established sepsis with antagonists of endogenous high-mobility group box 1

Despite significant advances in intensive care therapy and antibiotics, severe sepsis accounts for 9% of all deaths in the United States annually. The pathological sequelae of sepsis are characterized by a systemic inflammatory response, but experimental therapeutics that target specific early infla...

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Detalhes bibliográficos
Main Authors: Yang, Huan, Ochani, Mahendar, Li, Jianhua, Qiang, Xiaoling, Tanovic, Mahira, Harris, Helena E., Susarla, Srinivas M., Ulloa, Luis, Wang, Hong, DiRaimo, Robert, Czura, Christopher J., Wang, Haichao, Roth, Jesse, Warren, H. Shaw, Fink, Mitchell P., Fenton, Matthew J., Andersson, Ulf, Tracey, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314179/
https://ncbi.nlm.nih.gov/pubmed/14695889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2434651100
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