Pharmacological Stimulation of the Cholinergic Antiinflammatory Pathway

Efferent activity in the vagus nerve can prevent endotoxin-induced shock by attenuating tumor necrosis factor (TNF) synthesis. Termed the “cholinergic antiinflammatory pathway,” inhibition of TNF synthesis is dependent on nicotinic α-bungarotoxin-sensitive acetylcholine receptors on macrophages. Vag...

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Main Authors: Bernik, Thomas R., Friedman, Steven G., Ochani, Mahendar, DiRaimo, Robert, Ulloa, Luis, Yang, Huan, Sudan, Samridhi, Czura, Christopher J., Ivanova, Svetlana M., Tracey, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193742/
https://ncbi.nlm.nih.gov/pubmed/11901203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011714
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