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Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis

The innate immune system protects against infection and tissue injury through the specialized organs of the reticuloendothelial system, including the lungs, liver, and spleen. The central nervous system regulates innate immune responses via the vagus nerve, a mechanism termed the cholinergic antiinf...

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Detalhes bibliográficos
Main Authors: Huston, Jared M., Ochani, Mahendar, Rosas-Ballina, Mauricio, Liao, Hong, Ochani, Kanta, Pavlov, Valentin A., Gallowitsch-Puerta, Margot, Ashok, Mala, Czura, Christopher J., Foxwell, Brian, Tracey, Kevin J., Ulloa, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118357/
https://ncbi.nlm.nih.gov/pubmed/16785311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052362
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