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Regulation of HMGB1 release by inflammasomes

High mobility group box 1 (HMGB1) is an evolutionarily conserved non-histone chromatin-binding protein. During infection or injury, activated immune cells and damaged cells release HMGB1 into the extracellular space, where HMGB1 functions as a proinflammatory mediator and contributes importantly to...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Lu, Ben, Wang, Haichao, Andersson, Ulf, Tracey, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533838/
https://ncbi.nlm.nih.gov/pubmed/23483477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2118-2
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