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Regulation of HMGB1 release by inflammasomes
High mobility group box 1 (HMGB1) is an evolutionarily conserved non-histone chromatin-binding protein. During infection or injury, activated immune cells and damaged cells release HMGB1 into the extracellular space, where HMGB1 functions as a proinflammatory mediator and contributes importantly to...
Gespeichert in:
| Veröffentlicht in: | Protein Cell |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Higher Education Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4533838/ https://ncbi.nlm.nih.gov/pubmed/23483477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2118-2 |
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