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Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
Sepsis, a potentially fatal clinical syndrome, is mediated by an early (e.g., tumor necrosis factor and IL-1) and late [e.g., high mobility group B-1 (HMGB1)] proinflammatory cytokine response to infection. Specifically targeting early mediators has not been effective clinically, in part because pea...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129448/ https://ncbi.nlm.nih.gov/pubmed/12209006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192222999 |
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