Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification

Type IIA topoisomerases modify DNA topology by passing one segment of duplex DNA (transfer or T–segment) through a transient double-strand break in a second segment of DNA (gate or G–segment) in an ATP-dependent reaction. Type IIA topoisomerases decatenate, unknot and relax supercoiled DNA to levels...

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Hlavní autoři: Hardin, Ashley H., Sarkar, Susanta K., Seol, Yeonee, Liou, Grace F., Osheroff, Neil, Neuman, Keir C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141238/
https://ncbi.nlm.nih.gov/pubmed/21421557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr109
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