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Theoretical models of DNA topology simplification by type IIA DNA topoisomerases

It was discovered 12 years ago that type IIA topoisomerases can simplify DNA topology—the steady-state fractions of knots and links created by the enzymes are many times lower than the corresponding equilibrium fractions. Though this property of the enzymes made clear biological sense, it was not cl...

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Detalles Bibliográficos
Autor principal: Vologodskii, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691845/
https://ncbi.nlm.nih.gov/pubmed/19383879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp250
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