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Kinetic pathways of topology simplification by Type-II topoisomerases in knotted supercoiled DNA

The topological state of covalently closed, double-stranded DNA is defined by the knot type [Formula: see text] and the linking-number difference [Formula: see text] relative to unknotted relaxed DNA. DNA topoisomerases are essential enzymes that control the topology of DNA in all cells. In particul...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Ziraldo, Riccardo, Hanke, Andreas, Levene, Stephen D
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326819/
https://ncbi.nlm.nih.gov/pubmed/30476194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1174
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