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Transcriptional supercoiling boosts topoisomerase II-mediated knotting of intracellular DNA
Recent studies have revealed that the DNA cross-inversion mechanism of topoisomerase II (topo II) not only removes DNA supercoils and DNA replication intertwines, but also produces small amounts of DNA knots within the clusters of nucleosomes that conform to eukaryotic chromatin. Here, we examine ho...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6649788/ https://ncbi.nlm.nih.gov/pubmed/31165864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz491 |
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