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Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification
Type IIA topoisomerases modify DNA topology by passing one segment of duplex DNA (transfer or T–segment) through a transient double-strand break in a second segment of DNA (gate or G–segment) in an ATP-dependent reaction. Type IIA topoisomerases decatenate, unknot and relax supercoiled DNA to levels...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141238/ https://ncbi.nlm.nih.gov/pubmed/21421557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr109 |
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