Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification

Type II topoisomerases are essential enzymes that regulate DNA topology through a strand-passage mechanism. Some type II topoisomerases relax supercoils, unknot and decatenate DNA to below thermodynamic equilibrium. Several models of this non-equilibrium topology simplification phenomenon have been...

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Autores principales: Seol, Yeonee, Hardin, Ashley H., Strub, Marie-Paule, Charvin, Gilles, Neuman, Keir C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632123/
https://ncbi.nlm.nih.gov/pubmed/23460205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt136
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