טוען...
A small molecule probe induces a conformation in HIV TAR RNA capable of binding drug-like fragments
The HIV-1 TAR/Tat interaction is a potentially valuable target for treating HIV infection, but efforts to develop TAR-binding antiviral drugs have not yet yielded a successful candidate for clinical development. In this work, we describe a novel approach towards screening fragments against RNA that...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140652/ https://ncbi.nlm.nih.gov/pubmed/21763501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.039 |
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