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Development of Small Molecules with a Non-Canonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA

Small molecules that bind to RNA potently and specifically are relatively rare. The study of molecules that bind to the HIV-1 transactivation response (TAR) hairpin, a cis-acting HIV genomic element, has long been an important model system for the chemistry of targeting RNA. Here we report the synth...

詳細記述

保存先:
書誌詳細
出版年:J Med Chem
主要な著者: Abulwerdi, Fardokht A., Shortridge, Matthew D., Sztuba-Solinska, Joanna, Wilson, Robert, Le Grice, Stuart F. J., Varani, Gabriele, Schneekloth, John S.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525537/
https://ncbi.nlm.nih.gov/pubmed/28002966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01450
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