Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays

[Image: see text] Identifying small molecules that selectively bind to structured RNA motifs remains an important challenge in developing potent and specific therapeutics. Most strategies to find RNA-binding molecules have identified highly charged compounds or aminoglycosides that commonly have mod...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Sztuba-Solinska, Joanna, Shenoy, Shilpa R., Gareiss, Peter, Krumpe, Lauren R. H., Le Grice, Stuart F. J., O’Keefe, Barry R., Schneekloth, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227816/
https://ncbi.nlm.nih.gov/pubmed/24820959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja502754f
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