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Ligand-induced changes in 2-aminopurine fluorescence as a probe for small molecule binding to HIV-1 TAR RNA

Replication of human immunodeficiency virus type 1 (HIV-1) is regulated in part through an interaction between the virally encoded trans-activator protein Tat and the trans-activator responsive region (TAR) of the viral RNA genome. Because TAR is highly conserved and its interaction with Tat is requ...

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Detalhes bibliográficos
Main Authors: BRADRICK, THOMAS D., MARINO, JOHN P.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370632/
https://ncbi.nlm.nih.gov/pubmed/15273324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7620304
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