Wird geladen...
A small molecule probe induces a conformation in HIV TAR RNA capable of binding drug-like fragments
The HIV-1 TAR/Tat interaction is a potentially valuable target for treating HIV infection, but efforts to develop TAR-binding antiviral drugs have not yet yielded a successful candidate for clinical development. In this work, we describe a novel approach towards screening fragments against RNA that...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140652/ https://ncbi.nlm.nih.gov/pubmed/21763501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.039 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|