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Ligand-observed NMR techniques to probe RNA-small molecule interactions

A growing understanding of the structure and function of RNA has revealed it as a key regulator of gene expression and disease. A multitude of noncoding functions apart from the central roles of RNA in coding for and facilitating protein biogenesis has stimulated research into RNA as a pharmacologic...

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Publicado en:Methods Enzymol
Main Authors: Calabrese, David R., Connelly, Colleen M., Schneekloth, John S.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274943/
https://ncbi.nlm.nih.gov/pubmed/31239044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.05.030
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