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The RNR motif of B. subtilis RNase P protein interacts with both PRNA and pre-tRNA to stabilize an active conformer

Ribonuclease P (RNase P) catalyzes the metal-dependent 5′ end maturation of precursor tRNAs (pre-tRNAs). In Bacteria, RNase P is composed of a catalytic RNA (PRNA) and a protein subunit (P protein) necessary for function in vivo. The P protein enhances pre-tRNA affinity, selectivity, and cleavage ef...

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Autors principals: Koutmou, Kristin S., Day-Storms, Jeremy J., Fierke, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138560/
https://ncbi.nlm.nih.gov/pubmed/21622899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2742511
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