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Probing the architecture of the B. subtilis RNase P holoenzyme active site by cross-linking and affinity cleavage

Bacterial ribonuclease P (RNase P) is a ribonucleoprotein complex composed of one catalytic RNA (PRNA) and one protein subunit (P protein) that together catalyze the 5′ maturation of precursor tRNA. High-resolution X-ray crystal structures of the individual P protein and PRNA components from several...

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Detalhes bibliográficos
Main Authors: Niranjanakumari, Somashekarappa, Day-Storms, Jeremy J., Ahmed, Mahiuddin, Hsieh, John, Zahler, Nathan H., Venters, Ronald A., Fierke, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831860/
https://ncbi.nlm.nih.gov/pubmed/17299131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.308707
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