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Characterization of conserved sequence elements in eukaryotic RNase P RNA reveals roles in holoenzyme assembly and tRNA processing

RNase P is a ubiquitous endoribonuclease responsible for cleavage of the 5′ leader of precursor tRNAs (pre-tRNAs). Although the protein composition of RNase P holoenzymes varies significantly among Bacteria, Archaea, and Eukarya, the holoenzymes have essential RNA subunits with several sequences and...

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Autori principali: XIAO, SHAOHUA, DAY-STORMS, JEREMY J., SRISAWAT, CHATCHAWAN, FIERKE, CAROL A., ENGELKE, DAVID R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2005 by RNA Society 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370773/
https://ncbi.nlm.nih.gov/pubmed/15872187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7282205
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