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A divalent cation stabilizes the active conformation of the B. subtilis RNase P•pre-tRNA complex: a role for an inner-sphere metal ion in RNase P
Metal ions interact with RNA to enhance folding, stabilize structure and, in some cases, facilitate catalysis. Assigning functional roles to specifically bound metal ions presents a major challenge in analyzing the catalytic mechanisms of ribozymes. B. subtilis ribonuclease P (RNase P), composed of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2939038/ https://ncbi.nlm.nih.gov/pubmed/20434461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.050 |
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