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Disease-associated mutations in mitochondrial precursor tRNAs affect binding, m1R9 methylation, and tRNA processing by mtRNase P

Mitochondrial diseases linked to mutations in mitochondrial (mt) tRNA sequences are common. However, the contributions of these tRNA mutations to the development of diseases is mostly unknown. Mutations may affect interactions with (mt)tRNA maturation enzymes or protein synthesis machinery leading t...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:RNA
Asıl Yazarlar: Karasik, Agnes, Wilhelm, Catherine A., Fierke, Carol A., Koutmos, Markos
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962481/
https://ncbi.nlm.nih.gov/pubmed/33380464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.077198.120
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