A carregar...
The second coordination sphere of FIH controls hydroxylation
The factor inhibiting HIF (FIH) is a proximate oxygen sensor for human cells, hydroxylating Asn(803) within the α subunit of the hypoxia inducible factor (HIF). FIH is an α-ketoglutatrate (αKG) dependent, non-heme Fe(II) dioxygenase, in which Fe(II) is coordinated by a (His(2)Asp) facial triad, αKG,...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138472/ https://ncbi.nlm.nih.gov/pubmed/21456582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi102042t |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|