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Coordination changes and auto-hydroxylation of FIH-1: uncoupled O(2)-activation in a human hypoxia sensor
Hypoxia sensing is the generic term for pO(2)-sensing in humans and other higher organisms. These cellular responses to pO(2) are largely controlled by enzymes that belong to the Fe(II) α-ketoglutarate (αKG) dependent dioxygenase superfamily, including the human enzyme called the Factor Inhibiting H...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649026/ https://ncbi.nlm.nih.gov/pubmed/18805587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2008.07.018 |
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