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Inverse solvent isotope effects arising from substrate triggering in the factor inhibiting HIF (FIH-1)
Oxygen homeostasis plays a critical role in angiogenesis, erythropoiesis and cell metabolism. Oxygen homeostasis is set by the hypoxia inducible factor-1α (HIF-1α) pathway, which is controlled by Factor Inhibiting HIF-1α (FIH). FIH is a non-heme Fe(II), α-ketoglutarate dependent dioxygenase that inh...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059518/ https://ncbi.nlm.nih.gov/pubmed/23351038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3015482 |
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