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Synthesis and Activity of Thioether-Containing Analogues of the Complement Inhibitor Compstatin
Disulfide bonds are essential for the structural stability and biological activity of many bioactive peptides. However, these bonds are labile to reducing agents, which can limit the therapeutic utility of such peptides. Substitution of a disulfide bond with a reduction-resistant cystathionine bridg...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137721/ https://ncbi.nlm.nih.gov/pubmed/21520911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000378 |
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