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Structure-Kinetic Relationship Analysis of the Therapeutic Complement Inhibitor Compstatin

Compstatin is a 13-residue peptide that inhibits activation of the complement system by binding to the central component C3 and its fragments C3b and C3c. A combination of theoretical and experimental approaches has previously allowed us to develop analogs of the original compstatin peptide with up...

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Detalhes bibliográficos
Main Authors: Magotti, Paola, Ricklin, Daniel, Qu, Hongchang, Wu, You-Qiang, Kaznessis, Yiannis N., Lambris, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760637/
https://ncbi.nlm.nih.gov/pubmed/19658192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.972
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