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A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatin
Compstatin is a 13-residue cyclic peptide inhibitor of complement activation that was originally identified through phage-mediated presentation of a peptide library to C3b. Recent efforts to improve its activity have led to a rich dataset of complement analogs, with the most active analog being ~260...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995432/ https://ncbi.nlm.nih.gov/pubmed/17188878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.12.015 |
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