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Solution structure of Compstatin, a potent complement inhibitor.

The third component of complement, C3, plays a central role in activation of the classical, alternative, and lectin pathways of complement activation. Recently, we have identified a 13-residue cyclic peptide (named Compstatin) that specifically binds to C3 and inhibits complement activation. To inve...

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Autori principali: Morikis, D., Assa-Munt, N., Sahu, A., Lambris, J. D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143948/
https://ncbi.nlm.nih.gov/pubmed/9541394
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