Cargando...

Synthesis and Activity of Thioether-Containing Analogues of the Complement Inhibitor Compstatin

Disulfide bonds are essential for the structural stability and biological activity of many bioactive peptides. However, these bonds are labile to reducing agents, which can limit the therapeutic utility of such peptides. Substitution of a disulfide bond with a reduction-resistant cystathionine bridg...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Knerr, Patrick J., Tzekou, Apostolia, Ricklin, Daniel, Qu, Hongchang, Chen, Hui, van der Donk, Wilfred A., Lambris, John D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137721/
https://ncbi.nlm.nih.gov/pubmed/21520911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000378
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!