Llwytho...

Synthesis and Activity of Thioether-Containing Analogues of the Complement Inhibitor Compstatin

Disulfide bonds are essential for the structural stability and biological activity of many bioactive peptides. However, these bonds are labile to reducing agents, which can limit the therapeutic utility of such peptides. Substitution of a disulfide bond with a reduction-resistant cystathionine bridg...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Knerr, Patrick J., Tzekou, Apostolia, Ricklin, Daniel, Qu, Hongchang, Chen, Hui, van der Donk, Wilfred A., Lambris, John D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137721/
https://ncbi.nlm.nih.gov/pubmed/21520911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000378
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