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Synthesis and Activity of Thioether-Containing Analogues of the Complement Inhibitor Compstatin
Disulfide bonds are essential for the structural stability and biological activity of many bioactive peptides. However, these bonds are labile to reducing agents, which can limit the therapeutic utility of such peptides. Substitution of a disulfide bond with a reduction-resistant cystathionine bridg...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137721/ https://ncbi.nlm.nih.gov/pubmed/21520911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000378 |
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