A New Generation of Potent Complement Inhibitors of the Compstatin Family

Compstatin family peptides are potent inhibitors of the complement system and promising drug candidates against diseases involving under-regulated complement activation. Compstatin is a 13-residue cyclized peptide that inhibits cleavage of complement protein C3, preventing downstream complement acti...

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Главные авторы: López de Victoria, Aliana, Gorham, Ronald D., Bellows, Meghan L., Ling, Jun, Lo, David D., Floudas, Christodoulos A., Morikis, Dimitrios
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095715/
https://ncbi.nlm.nih.gov/pubmed/21352502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2011.01111.x
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