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Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function
Vesicular trafficking is crucial for bone resorption by osteoclasts, in particular for formation of the ruffled border membrane and for removal of the resultant bone degradation products by transcytosis. These processes are regulated by Rab family GTPases, whose activity is dependent on post-transla...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136943/ https://ncbi.nlm.nih.gov/pubmed/21776414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16488 |
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