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Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function

Vesicular trafficking is crucial for bone resorption by osteoclasts, in particular for formation of the ruffled border membrane and for removal of the resultant bone degradation products by transcytosis. These processes are regulated by Rab family GTPases, whose activity is dependent on post-transla...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Taylor, Adam, Mules, Emilie H, Seabra, Miguel C, Helfrich, Miep H, Rogers, Michael J, Coxon, Fraser P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136943/
https://ncbi.nlm.nih.gov/pubmed/21776414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16488
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