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Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function
Vesicular trafficking is crucial for bone resorption by osteoclasts, in particular for formation of the ruffled border membrane and for removal of the resultant bone degradation products by transcytosis. These processes are regulated by Rab family GTPases, whose activity is dependent on post-transla...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136943/ https://ncbi.nlm.nih.gov/pubmed/21776414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16488 |
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