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Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function
Vesicular trafficking is crucial for bone resorption by osteoclasts, in particular for formation of the ruffled border membrane and for removal of the resultant bone degradation products by transcytosis. These processes are regulated by Rab family GTPases, whose activity is dependent on post-transla...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136943/ https://ncbi.nlm.nih.gov/pubmed/21776414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16488 |
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