Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function

Vesicular trafficking is crucial for bone resorption by osteoclasts, in particular for formation of the ruffled border membrane and for removal of the resultant bone degradation products by transcytosis. These processes are regulated by Rab family GTPases, whose activity is dependent on post-transla...

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Detaylı Bibliyografya
Asıl Yazarlar: Taylor, Adam, Mules, Emilie H, Seabra, Miguel C, Helfrich, Miep H, Rogers, Michael J, Coxon, Fraser P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2011
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136943/
https://ncbi.nlm.nih.gov/pubmed/21776414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16488
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