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Impaired prenylation of Rab GTPases in the gunmetal mouse causes defects in bone cell function

Vesicular trafficking is crucial for bone resorption by osteoclasts, in particular for formation of the ruffled border membrane and for removal of the resultant bone degradation products by transcytosis. These processes are regulated by Rab family GTPases, whose activity is dependent on post-transla...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Taylor, Adam, Mules, Emilie H, Seabra, Miguel C, Helfrich, Miep H, Rogers, Michael J, Coxon, Fraser P
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136943/
https://ncbi.nlm.nih.gov/pubmed/21776414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16488
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