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Ras effector switching as a developmental strategy

Organisms pattern and specify cell fates with remarkably high fidelity and robustness, and cancer may be considered in part to be a disease of fate specification gone awry. During C. elegans vulval development an initial EGF signal prompts Ras to activate its canonical effector pathway, Raf-MEK-ERK,...

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Detalles Bibliográficos
Autor Principal: Reiner, David J
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136914/
https://ncbi.nlm.nih.gov/pubmed/21776412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.2.15775
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