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Ras Effector Switching Promotes Divergent Cell Fates in C. elegans Vulval Patterning
The C. elegans vulva is patterned by epidermal growth factor (EGF) activation of Ras to control 1° fate, and 1° fate induces antagonistic Notch-dependent 2° fate. Furthermore, a spatial EGF gradient, in addition to inducing 1° fate, directly contributes to 2° fate via an unknown pathway. We find tha...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028984/ https://ncbi.nlm.nih.gov/pubmed/21238927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.12.004 |
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