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Ras effector switching as a developmental strategy
Organisms pattern and specify cell fates with remarkably high fidelity and robustness, and cancer may be considered in part to be a disease of fate specification gone awry. During C. elegans vulval development an initial EGF signal prompts Ras to activate its canonical effector pathway, Raf-MEK-ERK,...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136914/ https://ncbi.nlm.nih.gov/pubmed/21776412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.2.15775 |
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