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Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

Ras (Rat sarcoma) protein is a central regulator of cell growth and proliferation. Mutations in the RAS gene are known to occur in human cancers and have been shown to contribute to carcinogenesis. In this study, we show that the multifunctional-autoprocessing repeats-in-toxin (MARTX) toxin-effector...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Antic, Irena, Biancucci, Marco, Zhu, Yueming, Gius, David R., Satchell, Karla J. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468845/
https://ncbi.nlm.nih.gov/pubmed/26051945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8396
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