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Macrophage Mal1 deficiency suppresses atherosclerosis in LDL-receptor null mice by activating PPARγ-regulated genes
OBJECTIVE: The adipocyte/macrophage fatty acid-binding proteins, aP2 (FABP4) and Mal1 (FABP5), are intracellular lipid chaperones that modulate systemic glucose metabolism, insulin sensitivity and atherosclerosis. Combined deficiency of aP2 and Mal1 has been shown to reduce the development of athero...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135083/ https://ncbi.nlm.nih.gov/pubmed/21474828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.225839 |
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