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α-Synuclein, Leucine-Rich Repeat Kinase-2, and Manganese in the Pathogenesis of Parkinson Disease

Parkinson disease (PD) is the most common movement disorder. It is characterized by bradykinesia, postural instability, resting tremor, and rigidity associated with the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Another pathological hallmark of PD is the presence...

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Detalles Bibliográficos
Main Authors: Covy, Jason P., Giasson, Benoit I.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134594/
https://ncbi.nlm.nih.gov/pubmed/21238487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2011.01.003
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