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α-Synuclein, Leucine-Rich Repeat Kinase-2, and Manganese in the Pathogenesis of Parkinson Disease

Parkinson disease (PD) is the most common movement disorder. It is characterized by bradykinesia, postural instability, resting tremor, and rigidity associated with the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Another pathological hallmark of PD is the presence...

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Autors principals: Covy, Jason P., Giasson, Benoit I.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134594/
https://ncbi.nlm.nih.gov/pubmed/21238487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2011.01.003
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